Supportive Oligonucleotide Technique (SOT)

Utilizing specialized gene sequences to disrupt cell replication

SOT involves the injection of a molecule that is complementary to a specific gene sequence within viruses, bacteria, or pathogens


SOT is an experimental antisense molecule therapy


SOT has the potential to block genetic expression that controls replication within pathogens, viruses, and bacteria

Frequently Asked Questions

View all FAQs  

  • Can Supportive Oligonucleotide Technique (SOT) be used for all types of infections?

    SOT may be indicated in cases of a wide variety of viruses, including various herpes viruses, Epstein Barr, cytomegalovirus, Hepatitis B, Hepatitis C, and Lyme (Borrelia bacterium) and specific Lyme co-infections. A positive infectious test result within the last 6 months is required.

  • Can Supportive Oligonucleotide Technique (SOT) be used in all types of cancer?

    No, SOT cannot be utilized in every type of cancer. SOT is not used in cases of encapsulated cancers, such as tumors of the brain or central nervous system, due to a lack of circulating tumour cells in the blood. Additionally, SOT may not be used in the presence of very large or high-risk tumours (due to potential of tumour lysis syndrome).

    For cases of cancer where SOT may be applicable, recent imaging results, as well as specific blood tests are required to confirm eligibility.

  • Is Supportive Oligonucleotide Technique (SOT) provided alone?

    No, SOT is typically used alongside other treatment methods. Additionally, dexamethasone and Pepcid are typically prescribed prior to the injections to aid in the effects of the injections. Your Doctor will review these prescriptions with you, along with any other supportive treatments they recommend.

  • Do I need to complete testing before Supportive Oligonucleotide Technique (SOT)?

    Specific diagnostic tests are required prior to receiving SOT. Testing requirements vary depending on current health conditions. At your initial visit, your Doctor will review diagnostic testing you have already completed, and determine further bloodwork or imaging they require.

  • Is Supportive Oligonucleotide Technique (SOT) covered by MSP or Extended Health Plans?

    An SOT injection is provided during a visit with your Naturopathic Doctor, and will be billed as such. If you qualify for Premium Assistance through MSP, you may qualify for a small percentage of your visit cost to be covered by MSP.

    Most Extended Health plans have coverage that can be applied to naturopathic visits; however, most plans have a limit to their coverage per year. We recommend contacting your insurance provider directly prior to your visit to determine your coverage.

  • Am I a candidate for Supportive Oligonucleotide Technique (SOT)?

    Only a practitioner trained in SOT can determine if it is applicable to your health concerns. Within your initial visit, Dr Alex Chan will review your medical history, including test results and imaging reports, and will order additional testing to determine if you are a good candidate for SOT.

  • How much does Supportive Oligonucleotide Technique (SOT) cost?

    The cost of SOT will vary depending on how many injections are provided. Our Patient Care Coordinators can provide a quote prior to booking an appointment.

  • What are the side effects of Supportive Oligonucleotide Technique (SOT)?

    Patients may experience mild side effects such as bruising, swelling, or tenderness at the site of treatment. Side effects following an injection can vary greatly depending on the severity of your health concerns and response to the injection. Your Doctor will do a full review of all potential side effects prior to your treatment.

  • How many Supportive Oligonucleotide Technique (SOT) injections are typically required?

    The response to SOT varies, depending on the overall health of the patient, severity and chronicity of health concerns. Once you begin treatment, your Doctor will be able to monitor how you respond and provide a better estimate of how many treatments may be required. However, no more than 3 full-dose injections or 6 half-dose injections will be provided within a year.

  • Do I need to see a Naturopathic Doctor to receive Supportive Oligonucleotide Technique (SOT)?

    Yes, currently SOT is only provided by Dr. Alex Chan, ND, within Integrative. A consultation with Dr. Alex Chan, as well as specific testing, is required to determine eligibility for the use of SOT.

    Book an appointment with Dr. Alex Chan

  • When is Supportive Oligonucleotide Technique (SOT) used?

    SOT may be a helpful component of your treatment plan if you have been diagnosed with certain types of cancer or specific infections. Learn more.

View all FAQs  

Ready to start your journey?
We're ready when you are.

We’re here to help you on your journey to optimal health. Select the option that best suits you to book your appointment now.
Popup disabled