Low Dose Allergen Immunotherapy (LDI/LDA)
Allergies, food sensitivities, and autoimmunity are reflective of a loss of immune ‘tolerance’; when our immune system loses tolerance we become highly reactive, experiencing reactions to otherwise benign substances such as foods, airborne particles, and even our own tissue.
Low Dose Allergen Immunotherapy (also known as LDI or LDA) aims to retrain the immune system, restoring tolerance to a hyperactive system. During LDI/LDA treatments, extremely dilute amounts of antigens are combined with an enzyme solution containing B-glucuronidase and injected intradermally into the skin of the forearm. The antigen combination may include extremely low dose amounts of inhalants, foods, chemicals, bacteria, and/or woods.
Applications of LDI/LDA include:
Many conditions and symptoms are related to a loss of immune tolerance. As a result, there are many cases in which an LDI/LDA treatment plan may be indicated. These include, but are not limited to:
- Seasonal allergies
- Asthma, chronic sinusitis, repeated ear infections
- Food allergies, food intolerances/sensitivities
- Chemical intolerances/sensitivities, histamine intolerance, anaphylaxis
- Eczema, contact dermatitis, urticaria
- Arthritis of any variety
- Irritable bowel syndrome (IBS)
- Interstitial cystitis
- Chronic fatigue syndrome (CFS), fibromyalgia
- Candida/fungal-related illness
- Autoimmune diseases or conditions including Crohn’s and Ulcerative Colitis
Health Benefits of Low Dose Allergen Immunotherapy (LDI/LDA)
Increased Immune Tolerance
The injections of antigens aim to recalibrate the immune system response to the antigens, resulting in reduced reactivity to many substances such as food, bacteria, and airborne allergens.
Reduction of Symptoms
Many symptoms we experience related to antigens – such as food sensitivities, airborne allergies, and chemicals – are due to a lack of immune tolerance. By regulating immune system activity, LDI/LDA therapy may reduce many immune-mediated symptoms.
An Integrative Approach to LDI/LDA
The LDI/LDA program is an integrative approach to immune regulation. Initially, it involves a course of injections, every 7-8 weeks. Depending on your case, your doctor may recommend a course of 3 or 5 injections, in addition to follow-up visits to monitor your response. Each patient is unique; your doctor will cater the LDI/LDA program to meet your specific needs. Your treatment program may also include:
- Dietary changes, especially within the ‘critical period’ of the day before, the day of, and the day after the injection
- Specific supplements and/or medications
- Intravenous nutrient support
What Does Your First Visit Look Like?
After completion of these steps, your injections and follow-up visits will be booked.
1. Complete Medical
& Lifestyle History
Your doctor will take a complete history, gathering details regarding your current and past health concerns, lifestyle, as well as current supplements and medications
If needed, your doctor will recommend additional tests, either at Integrative or with your medical doctor. They may requisition results from tests you’ve completed in the past
3. Outline of the Program
If your doctor believes you are a good candidate for LDI/LDA, they will review the entire program with you, including scheduling, changes to medications and/or supplements, and dietary changes. At this time, they will also recommend either a 3-injection or a 5-injection treatment program
Your doctor will discuss potential side effects, contraindications, and frequently asked questions of the LDI/LDA program prior to any treatment.
Your Program Will Include the Following:
Package 1 / Basic LDI/LDA Treatment
Initial consult + 3 injections + 1 follow up
Package 2 / Advanced LDI/LDA Treatment
Initial consult + 5 injections + 2 follow ups
Learn More about LDI/LDA
Continue reading about the Low-Dose Allergen Immunotherapy program on the Integrative blog: Retrain Your Immune System with Low-Dose Allergen Immunotherapy.